منابع مشابه
Motor Control: The Curious Case of Cerebrospinal-Fluid-Contacting Neurons
Since their discovery almost a century ago, the functions of the cerebrospinal-fluid-contacting neurons have remained elusive: a new study paves the way towards understanding how these unusual spinal cord neurons regulate motor activity.
متن کاملFine structures of the cerebrospinal fluid-contacting neurons in the hypothalamus of the lamprey, Lampetra japonica.
In the preoptic, infundibular and posterior recesses of the lamprey, Lampetra japonica cerebrospinal fluid (CSF)-contacting neurons are distributed much more abundantly than in higher vertebrates. They are classified into three different types on the basis of their granules size or electron density: type 1 containing round dense granules of large size (180--230 nm in diameter), type 2 containin...
متن کاملOpioid peptides, CRF, and urocortin in cerebrospinal fluid-contacting neurons in Xenopus laevis.
The presence of the opioids, beta-endorphin, met-enkephalin, and endomorphin, and of corticotropin-releasing factor (CRF) and the CRF family member, urocortin (Ucn), is described in cerebrospinal fluid-contacting neurons in the brain of the amphibian, Xenopus laevis.
متن کاملThe late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord.
Considerable progress has been made in understanding the mechanisms that control the production of specialized neuronal types. However, how the timing of differentiation contributes to neuronal diversity in the developing spinal cord is still a pending question. In this study, we show that cerebrospinal fluid-contacting neurons (CSF-cNs), an anatomically discrete cell type of the ependymal area...
متن کاملCerebrospinal fluid-contacting nucleus mediates nociception via release of fractalkine
Increasing evidence suggests that the cerebrospinal fluid-contacting nucleus (CSF-contacting nucleus) mediates the transduction and regulation of pain signals. However, the precise molecular mechanisms remain unclear. Studies show that release of fractalkine (FKN) from neurons plays a critical role in nerve injury-related pain. We tested the hypothesis that release of FKN from the CSF-contacting...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2017
ISSN: 0960-9822
DOI: 10.1016/j.cub.2017.09.017